Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | C1S | P09871 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22042765 | 0.98 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CPLAUC1S | |
| SCHEMBL28079692 | 0.77 | LMNA (0.39) | — | |
| SCHEMBL1855352 | 0.75 | KDM4E (0.40) | ADRA2AADRA2BADRA2CPLAUHTT | |
| SCHEMBL24143680 | 0.75 | IDO1 (0.30) | IDO1 | |
| SCHEMBL8975471 | 0.73 | NPC1 (0.41) | KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL22042761 | 0.73 | IDO1 (0.32) | C1SKMT2AIDO1 | |
| Methane SCHEMBL26985795 | 0.73 | KDM4E (0.39) | ADRA2AADRA2BADRA2CPLAUHTT | |
| SCHEMBL17395056 | 0.71 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CPLAUHTT | |
| SCHEMBL17395054 | 0.71 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CPLAUHTT | |
| SCHEMBL1179705 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043615-B2 | Fluorine-containing pyrimidine compound and method for manufacturing the same | UNIMATEC CO., LTD. (JP) | 2024-07-23 | — | — | US | disclosed |
| US-12043615-B2 | Fluorine-containing pyrimidine compound and method for manufacturing the same | UNIMATEC CO., LTD. (JP) | 2024-07-23 | — | — | US | disclosed |
| US-20210403455-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND METHOD FOR MANUFACTURING THE SAME | UNIMATEC CO., LTD. (JP) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043615-B2 | Fluorine-containing pyrimidine compound and method for manufacturing the same | CNOT1, NUDT1, XRN2 | ADRA2A 1258/4885ADRA2B 2008/4885ADRA2C 2580/4885 |
| US-20210403455-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND METHOD FOR MANUFACTURING THE SAME | CNOT1, NUDT1, XRN2 | ADRA2A 1258/4885ADRA2B 2008/4885ADRA2C 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.