Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957556 | 0.82 | S1PR4 (0.60) | S1PR4MAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL2798909 | 0.76 | S1PR4 (0.59) | S1PR4MAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL29684617 | 0.71 | S1PR4 (0.67) | S1PR4MAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL19174959 | 0.71 | S1PR4 (0.67) | S1PR4MAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL13812975 | 0.70 | S1PR4 (0.55) | S1PR4MAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL363493 | 0.70 | S1PR4 (0.64) | S1PR4MAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL29707208 | 0.69 | NPC1 (0.79) | MAPTLMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1127097 | 0.69 | NPC1 (0.79) | MAPTLMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL357386 | 0.69 | S1PR4 (0.59) | S1PR4MAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL18347875 | 0.68 | S1PR4 (0.50) | S1PR4MAPTLMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005961-A1 | COMPOUNDS HAVING A PLURALITY OF NITROGENOUS SUBSTITUENTS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-12 | — | — | WO | disclosed |