Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 9/20 | 0.44 |
| ▸ | PPARA | Q07869 | 9/20 | 0.44 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959540 | 0.83 | PPARG (0.53) | PPARGPPARASUV39H2DRD2SIGMAR1 | |
| SCHEMBL7963688 | 0.83 | DRD2 (0.47) | PPARGPPARASUV39H2DRD2SIGMAR1 | |
| SCHEMBL7963831 | 0.83 | DRD2 (0.42) | PPARGPPARADRD2SIGMAR1ALDH1A1 | |
| SCHEMBL2928576 | 0.81 | HTR6 (0.44) | PPARGPPARADRD2SIGMAR1 | |
| SCHEMBL7949222 | 0.80 | DRD2 (0.49) | PPARGPPARASUV39H2DRD2SIGMAR1 | |
| SCHEMBL7961255 | 0.80 | DRD2 (0.52) | PPARGPPARASUV39H2DRD2SIGMAR1 | |
| SCHEMBL7960280 | 0.79 | DRD2 (0.46) | PPARGPPARASUV39H2DRD2SIGMAR1 | |
| SCHEMBL7959566 | 0.79 | PPARG (0.54) | PPARGPPARASUV39H2DRD2SIGMAR1 | |
| SCHEMBL7964138 | 0.78 | DRD2 (0.54) | PPARGPPARASUV39H2DRD2SIGMAR1 | |
| SCHEMBL7957644 | 0.78 | DRD2 (0.61) | PPARGPPARADRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |