Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 12/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963219 | 0.88 | NPY1R (0.75) | NPY1RSMN1; SMN2L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7958736 | 0.86 | NPY1R (0.71) | NPY1RTP53SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7949187 | 0.85 | NPY1R (0.79) | NPY1RSMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL7956905 | 0.84 | NPY1R (0.83) | NPY1RKMT2AALDH1A1HTTMEN1 | |
| SCHEMBL7963164 | 0.83 | NPY1R (1.00) | NPY1RSMN1; SMN2KMT2A | |
| SCHEMBL7956724 | 0.82 | NPY1R (0.75) | NPY1RTP53KMT2A | |
| SCHEMBL7959104 | 0.81 | NPY1R (0.73) | NPY1RSMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL7959050 | 0.81 | NPY1R (0.87) | NPY1RTP53SMN1; SMN2KMT2A | |
| SCHEMBL7958925 | 0.80 | NPY1R (0.71) | NPY1RL3MBTL1KMT2AHTR5A | |
| SCHEMBL7957137 | 0.79 | NPY1R (0.69) | NPY1RL3MBTL1KMT2AALDH1A1HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789688-A4 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0789688-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1997009308-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |