Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 4/20 | 0.31 |
| ▸ | IDH2 | P48735 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970291 | 0.76 | TP53 (0.44) | NFE2L2CYP3A4TSHRCYP1A2KDM4E | |
| SCHEMBL7968285 | 0.73 | NFE2L2 (0.53) | NFE2L2CYP3A4TSHRKDM4EALDH1A1 | |
| SCHEMBL1989599 | 0.69 | — | — | |
| SCHEMBL7969857 | 0.68 | NFE2L2 (0.49) | NFE2L2CYP1A2MEN1MAPTKMT2A | |
| SCHEMBL2093323 | 0.67 | RAPGEF4 (0.43) | RAPGEF4TSHRCYP1A2CYP2A6KDM4E | |
| SCHEMBL7969643 | 0.66 | NFE2L2 (0.38) | NFE2L2CYP3A4TSHRALDH1A1MAPT | |
| SCHEMBL864373 | 0.65 | — | — | |
| SCHEMBL22579286 | 0.65 | — | — | |
| SCHEMBL22392916 | 0.65 | — | — | |
| SCHEMBL29953522 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |