Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958691 | 0.88 | ALDH1A1 (0.46) | PARP1NR3C1ALDH1A1HPGDTSHR | |
| SCHEMBL6979942 | 0.86 | TSHR (0.38) | PARP1ALDH1A1HPGDTSHRMEN1 | |
| SCHEMBL6979149 | 0.85 | PARP1 (0.40) | PARP1NR3C1ALDH1A1HPGDTSHR | |
| SCHEMBL6982610 | 0.84 | ALDH1A1 (0.40) | PARP1NR3C1ALDH1A1HPGDTSHR | |
| SCHEMBL6985998 | 0.82 | NR3C1 (0.47) | PARP1NR3C1ALDH1A1HPGDTSHR | |
| SCHEMBL7956609 | 0.81 | NR3C1 (0.44) | PARP1NR3C1ALDH1A1HPGDTSHR | |
| SCHEMBL6984728 | 0.81 | TP53 (0.44) | PARP1NR3C1ALDH1A1HPGDTSHR | |
| SCHEMBL6977634 | 0.80 | NR3C1 (0.53) | NR3C1ALDH1A1HPGDTSHRMEN1 | |
| SCHEMBL6984161 | 0.80 | PARP1 (0.39) | PARP1NR3C1ALDH1A1HPGDTSHR | |
| SCHEMBL6986006 | 0.79 | NR3C1 (0.46) | PARP1NR3C1ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |