Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954897 | 0.91 | HTR7 (0.56) | HTR7NPSR1TTRKDM4EHSD17B10 | |
| SCHEMBL7960663 | 0.86 | SMN1; SMN2 (0.52) | HTR7NPSR1TTRKDM4EHSD17B10 | |
| SCHEMBL7956815 | 0.86 | HTR7 (0.66) | HTR7NPSR1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7964562 | 0.85 | NPC1 (0.51) | HTR7NPSR1TTRKDM4EHSD17B10 | |
| SCHEMBL7947807 | 0.85 | HTR7 (0.56) | HTR7NPSR1TTRKDM4EHSD17B10 | |
| SCHEMBL7961683 | 0.85 | CASP3 (0.51) | HTR7NPSR1TTRKDM4EHSD17B10 | |
| Irampanel SCHEMBL678128 | 0.85 | HTR7 (0.63) | HTR7NPSR1TTRKDM4EHSD17B10 | |
| SCHEMBL7947650 | 0.84 | SMN1; SMN2 (0.52) | HTR7NPSR1TTRKDM4EHSD17B10 | |
| Irampanel SCHEMBL6879876 | 0.84 | HTR7 (0.62) | HTR7NPSR1TTRKDM4EHSD17B10 | |
| SCHEMBL7962019 | 0.84 | NPC1 (0.56) | HTR7NPSR1TTRKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |