Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | PTGIR | P43119 | 7/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956749 | 0.84 | PTGIR (0.57) | PSMB8PSMB5PTGIRTBXA2RMEN1 | |
| SCHEMBL7956750 | 0.76 | PTGIR (0.61) | PSMB8PSMB5PTGIRTBXA2RALDH1A1 | |
| SCHEMBL7960429 | 0.75 | DAO (0.40) | PSMB8PSMB5PTGIRTBXA2RALDH1A1 | |
| SCHEMBL7963254 | 0.74 | PTGIR (0.47) | PSMB8PSMB5HTR1APTGIRTBXA2R | |
| SCHEMBL7956736 | 0.73 | PSMB8 (0.41) | PSMB8PSMB5HTR1APTGIRTBXA2R | |
| SCHEMBL5234354 | 0.73 | ALDH1A1 (0.46) | PSMB8PSMB5HTR1APTGIRTBXA2R | |
| SCHEMBL4130976 | 0.73 | PSMB8 (0.46) | PSMB8PSMB5HTR1APTGIRTBXA2R | |
| SCHEMBL5504988 | 0.73 | TAAR1 (0.53) | PSMB8PSMB5HTR1APTGIRTBXA2R | |
| SCHEMBL4136821 | 0.73 | MEN1 (0.46) | PSMB8PSMB5HTR1APTGIRTBXA2R | |
| SCHEMBL11297234 | 0.72 | HTR2A (0.52) | PSMB8PSMB5LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |