Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | PTGIR | P43119 | 8/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963020 | 0.83 | PTGIR (0.54) | PSMB8PSMB5ALDH1A1HPGDPTGIR | |
| SCHEMBL7963254 | 0.80 | PTGIR (0.47) | PSMB8PSMB5ALDH1A1LMNAMEN1 | |
| SCHEMBL7958890 | 0.73 | PSMB8 (0.43) | PSMB8PSMB5ALDH1A1LMNAMEN1 | |
| SCHEMBL806348 | 0.72 | ALDH1A1 (0.54) | PSMB8PSMB5ALDH1A1LMNAMEN1 | |
| SCHEMBL7953106 | 0.70 | ALDH1A1 (0.53) | PSMB8PSMB5ALDH1A1LMNAMEN1 | |
| SCHEMBL7962995 | 0.70 | ALDH1A1 (0.49) | PSMB8PSMB5ALDH1A1LMNAMEN1 | |
| SCHEMBL7958885 | 0.70 | ALDH1A1 (0.45) | PSMB8PSMB5ALDH1A1LMNAMEN1 | |
| SCHEMBL7948483 | 0.69 | PSMB8 (0.56) | PSMB8PSMB5ALDH1A1LMNAMEN1 | |
| SCHEMBL4136821 | 0.68 | MEN1 (0.46) | PSMB8PSMB5ALDH1A1LMNAMEN1 | |
| SCHEMBL5234354 | 0.68 | ALDH1A1 (0.46) | PSMB8PSMB5ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |