Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828924 | 0.85 | BTK (0.65) | BTKEPHX1KMT2AL3MBTL1 | |
| SCHEMBL6883716 | 0.85 | BTK (0.65) | BTKEPHX1KMT2AL3MBTL1 | |
| SCHEMBL6640171 | 0.85 | BTK (0.65) | BTKEPHX1KMT2AL3MBTL1 | |
| SCHEMBL6883712 | 0.85 | BTK (0.65) | BTKEPHX1KMT2AL3MBTL1 | |
| SCHEMBL6640571 | 0.85 | BTK (0.65) | BTKEPHX1KMT2AL3MBTL1 | |
| SCHEMBL28047884 | 0.82 | BTK (0.42) | BTKNPSR1EPHX1HPGDKMT2A | |
| SCHEMBL6962092 | 0.82 | EPHX1 (0.50) | BTKEPHX1EPHX2 | |
| SCHEMBL6962087 | 0.82 | EPHX1 (0.50) | BTKEPHX1EPHX2 | |
| SCHEMBL8162383 | 0.81 | EPHX1 (0.44) | BTKNPSR1EPHX1HPGDKMT2A | |
| SCHEMBL7790384 | 0.80 | BTK (0.51) | BTKNPSR1EPHX1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194409-B1 | SERINE PROTEASE INHIBITOR; BIOAVAILABILITY WHEN ADMINISTERED BY MOUTH | AKZO NOBEL N.V. (NL) | 2001-02-27 | — | — | US | disclosed |