Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.58 |
| ▸ | HTR7 | P34969 | 3/20 | 0.51 |
| ▸ | SOD1 | P00441 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 5/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5009446 | 0.74 | HTR1A (0.72) | HTR1AHTR7SOD1KMT2ADRD4 | |
| SCHEMBL7957628 | 0.74 | HTR1A (0.54) | HTR1AHTR7SOD1DRD4DRD2 | |
| SCHEMBL7959076 | 0.71 | HTR1A (0.56) | HTR1AHTR7SOD1KMT2ADRD4 | |
| SCHEMBL18823660 | 0.71 | HTR1A (0.56) | HTR1A | |
| SCHEMBL15996827 | 0.70 | HTR1A (0.66) | HTR1AHTR7SOD1KMT2ADRD4 | |
| SCHEMBL7960090 | 0.69 | HTR1A (0.54) | HTR1AHTR7SOD1KMT2ADRD4 | |
| SCHEMBL28930040 | 0.67 | ALDH1A1 (0.66) | HTR1ASOD1KMT2ADRD4DRD2 | |
| Hydrochloric Acid SCHEMBL6598101 | 0.67 | HTR1A (0.98) | HTR1AHTR7SOD1KMT2ADRD4 | |
| SCHEMBL3200010 | 0.67 | CACNA1G (0.69) | HTR1AHTR7DRD4DRD2DRD3 | |
| SCHEMBL7949281 | 0.67 | CACNA1G (0.69) | HTR1AHTR7DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |