Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795771 | 0.90 | HPGD (0.47) | KDM4EPKMGPR119HPGDRECQL | |
| SCHEMBL15477299 | 0.83 | CYP2C9 (0.35) | EPHX1 | |
| SCHEMBL190460 | 0.81 | NR1H2 (0.61) | NR1H2KDM4EPKMGPR119HPGD | |
| SCHEMBL6218596 | 0.81 | NR1H2 (0.61) | NR1H2KDM4EPKMGPR119HPGD | |
| SCHEMBL4729255 | 0.79 | NR1H2 (0.59) | NR1H2KDM4EPKMGPR119HPGD | |
| SCHEMBL20071875 | 0.78 | HPGD (0.50) | NR1H2KDM4EPKMGPR119HPGD | |
| SCHEMBL796239 | 0.78 | HPGD (0.53) | NR1H2KDM4EPKMGPR119HPGD | |
| SCHEMBL17220200 | 0.78 | HPGD (0.45) | KDM4EPKMGPR119HPGDRECQL | |
| SCHEMBL27600055 | 0.77 | NR1H2 (0.60) | NR1H2KDM4EPKMGPR119HPGD | |
| SCHEMBL26635122 | 0.76 | GPR119 (0.58) | KDM4EPKMGPR119HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-A1 | TRIAZINE-OXADIAZOLES | Novartis AG (CH) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |