Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312106 | 0.80 | ALDH1A1 (0.38) | MEN1RAB9AKMT2AHPGDALDH1A1 | |
| SCHEMBL9152723 | 0.78 | MAOB (0.45) | MAOBSLC22A6SLC22A8MEN1RAB9A | |
| SCHEMBL1637752 | 0.78 | GAA (0.43) | RAB9AALDH1A1MAPTMAPK1TAAR1 | |
| SCHEMBL7956535 | 0.77 | MAOB (0.43) | MAOBSLC22A6SLC22A8MEN1RAB9A | |
| SCHEMBL1636127 | 0.77 | ACHE (0.33) | MEN1KMT2AALDH1A1CYP3A4TSHR | |
| SCHEMBL15474681 | 0.75 | MAOB (0.42) | MAOBSLC22A6SLC22A8MEN1RAB9A | |
| SCHEMBL1637735 | 0.75 | NPC1 (0.33) | RAB9AALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL1299740 | 0.75 | MAOB (0.42) | MAOBSLC22A6SLC22A8MEN1RAB9A | |
| SCHEMBL28821414 | 0.75 | POLB (0.38) | MAPTTAAR1POLB | |
| SCHEMBL1095882 | 0.74 | GAA (0.43) | MEN1RAB9AKMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |