Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871966 | 0.95 | TDP1 (0.49) | TDP1ADRB2HTR1AADRB1DRD2 | |
| SCHEMBL18687780 | 0.88 | ADRB2 (0.49) | TDP1ADRB2HTR1ADRD2CA12 | |
| SCHEMBL6874085 | 0.88 | NQO2 (0.51) | TDP1ADRB2HTR1AADRB1DRD2 | |
| SCHEMBL12634899 | 0.87 | TDP1 (0.60) | TDP1DRD2CA12CA1CA2 | |
| SCHEMBL8985088 | 0.84 | MTNR1A (0.54) | ADRB2HTR1AADRB1DRD2 | |
| SCHEMBL14092158 | 0.83 | DRD2 (0.46) | TDP1ADRB2HTR1AADRB1DRD2 | |
| SCHEMBL15146019 | 0.82 | CA12 (0.53) | TDP1ADRB2HTR1ADRD2CA12 | |
| SCHEMBL18687756 | 0.82 | ADRB2 (0.51) | TDP1ADRB2HTR1ADRD2CA12 | |
| SCHEMBL16158175 | 0.82 | TDP1 (0.53) | TDP1DRD2CA12CA1CA2 | |
| SCHEMBL30898271 | 0.82 | TDP1 (0.53) | TDP1DRD2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274584-B1 | PEPTIDE DERIVATIVES; BIOAVAILABILITY; ENZYME RESISTANCE; MILK AND WOOL PRODUCTION | NOVO NORDISK A/S (DK) | 2001-08-14 | — | — | US | disclosed |