Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.32 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.32 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5773960 | 0.99 | KDM4E (0.34) | KDM4EALDH1A1CHRNA7BCHETRPC3 | |
| SCHEMBL5774286 | 0.89 | STK17A (0.30) | MEN1KMT2ASMN1; SMN2TAAR1PTPN11 | |
| SCHEMBL5773791 | 0.88 | ACHE (0.30) | PTPN11 | |
| Hydrochloric Acid SCHEMBL5775437 | 0.87 | — | — | |
| SCHEMBL5776304 | 0.87 | PRCP (0.32) | — | |
| Hydrochloric Acid SCHEMBL5776452 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL5775517 | 0.85 | MMP12 (0.32) | — | |
| SCHEMBL5773246 | 0.83 | CHRNA7 (0.34) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL5772701 | 0.82 | CHRNA7 (0.33) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL8125138 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187777-B1 | PYRROLO(3,2-D)PYRIMIDINE DERIVATIVES; NEUROPEPTIDE Y AND CORTICOTROPIN RELEASING FACTOR MODULATORS; DIETETICS; ANTIDIABETIC, ANTIINFLAMMATORY, AND ANTITUMOR AGENTS | AMGEN INC. | 2001-02-13 | — | — | US | claimed |