Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.54 |
| ▸ | DRD2 | P14416 | 8/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949619 | 0.89 | DRD2 (0.53) | CCR1DRD2DRD3ADRA1A | |
| SCHEMBL7960074 | 0.89 | DRD2 (0.62) | CCR1DRD2ADRA1A | |
| SCHEMBL7957456 | 0.88 | CCR1 (0.56) | CCR1DRD2MEN1KMT2AADRA1A | |
| SCHEMBL7963515 | 0.83 | CCR1 (0.58) | CCR1DRD2KMT2AADRA1AADRA1D | |
| SCHEMBL7949042 | 0.82 | CCR1 (0.52) | CCR1DRD2 | |
| SCHEMBL7960236 | 0.81 | DRD2 (0.63) | CCR1DRD2DRD4DRD3ADRA1A | |
| SCHEMBL7963903 | 0.81 | DRD2 (0.50) | CCR1DRD2DRD4 | |
| SCHEMBL7957164 | 0.81 | DRD2 (0.56) | CCR1DRD2 | |
| SCHEMBL7964042 | 0.79 | DRD2 (0.46) | CCR1DRD2DRD4DRD3 | |
| SCHEMBL8568579 | 0.79 | OPRM1 (0.58) | CCR1DRD2DRD4DRD3ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |