Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | KLK1 | P06870 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 2/20 | 0.45 |
| ▸ | CCND1 | P24385 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
| ▸ | BID | P55957 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958451 | 0.84 | HTR2C (0.49) | HTR2CKLKB1KLK1MCL1HTR6 | |
| SCHEMBL7958387 | 0.81 | HTR2C (0.51) | HTR2CKLKB1KLK1MCL1HTR6 | |
| SCHEMBL7958950 | 0.79 | KLKB1 (0.49) | KLKB1KLK1CDK4CCND1MCL1 | |
| SCHEMBL8616920 | 0.79 | HTR6 (0.60) | HTR2CHTR6 | |
| SCHEMBL7959220 | 0.77 | MCL1 (0.59) | KLKB1KLK1BCL2L1MCL1HTR6 | |
| SCHEMBL28186282 | 0.77 | CDK4 (0.77) | HTR2CCDK4CCND1P2RX7 | |
| SCHEMBL4651322 | 0.77 | HTR2C (0.65) | HTR2CCDK4CCND1 | |
| SCHEMBL7959061 | 0.77 | HTR2C (0.54) | HTR2CCDK4CCND1MCL1HTR6 | |
| SCHEMBL27587633 | 0.77 | HTR2C (0.56) | HTR2CMCL1HTR6 | |
| SCHEMBL3245076 | 0.75 | HTR2C (0.66) | HTR2CCDK4CCND1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1092639-C | Benzene-fused heterocyclic derivative and use thereof | TORAY INDUSTRIES (JP) | 2002-10-16 | — | — | CN | disclosed |
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| CN-1148381-A | Benzene-fused heterocyclic derivative and use thereof | TORAY INDUSTRIES (JP) | 1997-04-23 | — | — | CN | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |