SCHEMBL7960135

SCHEMBL7960135

COC(=O)C1(NC(=O)Cc2c(C)cc(OC)cc2C)CCCC(C)C1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.34
ALDH1A1 P00352 2/20 0.34
APOBEC3A P31941 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
LPAR1 Q92633 1/20 0.33
MAPT P10636 1/20 0.33
P2RX7 Q99572 1/20 0.32
EPHX2 P34913 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KMT2A Q03164 4/20 0.31
MEN1 O00255 2/20 0.31
GAA P10253 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7964124 0.91 LPAR1 (0.40) HPGDALDH1A1APOBEC3AAPOBEC3GLPAR1
SCHEMBL8907276 0.91 MAPT (0.34) HPGDALDH1A1LPAR1MAPTP2RX7
SCHEMBL7958124 0.86 SMN1; SMN2 (0.35) HPGDALDH1A1APOBEC3AAPOBEC3GLPAR1
SCHEMBL7960533 0.86 ALDH1A1 (0.45) HPGDALDH1A1APOBEC3AAPOBEC3GP2RX7
SCHEMBL7957870 0.86 LPAR1 (0.35) HPGDLPAR1MAPTKMT2AMEN1
SCHEMBL7964591 0.86 MAPT (0.38) HPGDALDH1A1MAPTL3MBTL1KMT2A
SCHEMBL7960343 0.86 HPGD (0.34) HPGDALDH1A1APOBEC3AAPOBEC3GLPAR1
SCHEMBL7950104 0.85 MAPT (0.40) HPGDALDH1A1MAPTL3MBTL1KMT2A
SCHEMBL7949759 0.85 MAPT (0.40) HPGDALDH1A1MAPTL3MBTL1KMT2A
SCHEMBL7958068 0.85 MAPT (0.40) HPGDALDH1A1MAPTL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172255-B1 INSECTICIDES; MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
US-5830826-A Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides BAYER AKTIENGESELLSCHAFT (DE) 1998-11-03 US disclosed