Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | GLB1 | P16278 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653074 | 0.81 | THRB (0.67) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL3657084 | 0.81 | THRB (0.67) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL1644389 | 0.78 | HPGD (0.41) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL1942341 | 0.76 | MEN1 (0.61) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL1608876 | 0.76 | HPGD (0.63) | RECQLTDP1ALDH1A1HPGDBRCA1 | |
| Hydrochloric Acid SCHEMBL25316086 | 0.75 | HPGD (0.62) | RECQLTDP1ALDH1A1HPGDBRCA1 | |
| SCHEMBL4022672 | 0.73 | ALDH1A1 (0.43) | RECQLTDP1ALDH1A1HPGDBRCA1 | |
| SCHEMBL7970168 | 0.72 | FTO (0.60) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL1608886 | 0.71 | HPGD (0.45) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL1643388 | 0.71 | HPGD (0.40) | THRBRECQLTDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6229055-B1 | SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES | MOLECULAR PROBES, INC. | 2001-05-08 | — | — | US | disclosed |
| US-6162931-A | Fluorinated xanthene derivatives | MOLECULAR PROBES, INC. (US) | 2000-12-19 | — | — | US | disclosed |