Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140040 | 0.85 | CHEK2 (0.34) | BRD4CHEK2TSPOEGFRMEN1 | |
| SCHEMBL7970581 | 0.80 | F9 (0.40) | BRD4CHEK2MEN1KMT2AHPSE | |
| SCHEMBL20307854 | 0.80 | CA12 (0.39) | BRD4CHEK2MEN1KMT2AMAPT | |
| SCHEMBL7973155 | 0.80 | F9 (0.39) | BRD4CHEK2EGFRMEN1KMT2A | |
| SCHEMBL7980011 | 0.79 | CHEK2 (0.38) | BRD4CHEK2EGFRMEN1KMT2A | |
| SCHEMBL7973947 | 0.78 | CHEK2 (0.36) | BRD4CHEK2EGFRMEN1KMT2A | |
| SCHEMBL7973202 | 0.78 | F9 (0.39) | BRD4CHEK2MEN1KMT2AHPSE | |
| SCHEMBL20307724 | 0.77 | NPBWR1 (0.36) | BRD4CHEK2MEN1KMT2AHPSE | |
| SCHEMBL20307800 | 0.77 | ALOX5 (0.39) | BRD4CHEK2MEN1KMT2AMAPT | |
| SCHEMBL7960714 | 0.76 | CHEK2 (0.39) | CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |