Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.64 |
| ▸ | NOS1 | P29475 | 3/20 | 0.64 |
| ▸ | NOS3 | P29474 | 2/20 | 0.64 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7960401 | 0.99 | NOS2 (0.63) | NOS2NOS1NOS3NAMPTALDH1A1 | |
| SCHEMBL7938165 | 0.86 | NOS2 (0.70) | NOS2NOS1NOS3ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL8379762 | 0.85 | NOS2 (0.69) | NOS2NOS1NOS3ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL8379709 | 0.79 | NOS2 (0.61) | NOS2NOS1NOS3ALDH1A1GAA | |
| SCHEMBL7960106 | 0.79 | NOS2 (0.67) | NOS2NOS1NOS3ALDH1A1MAPT | |
| SCHEMBL7964756 | 0.79 | NOS2 (0.59) | NOS2NOS1NOS3ALDH1A1MAPT | |
| SCHEMBL7938121 | 0.77 | NOS2 (0.81) | NOS2NOS1NOS3ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL8381053 | 0.77 | NOS2 (0.79) | NOS2NOS1NOS3ALDH1A1GAA | |
| SCHEMBL7931761 | 0.76 | NOS2 (0.74) | NOS2NOS1NOS3ALDH1A1GAA | |
| SCHEMBL7940883 | 0.76 | NOS2 (1.00) | NOS2NOS1NOS3ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303613-B1 | AS NITRIC OXIDE SYNTHASE INHIBITOR USEFUL IN THERAPY OR PROPHYLAXIS OF INFLAMMATORY DISEASE AND PAIN | ASTRAZENECA AB (SE) | 2001-10-16 | — | — | US | disclosed |