Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961707 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2 | |
| SCHEMBL5544959 | 0.69 | SMN1; SMN2 (0.65) | SMN1; SMN2 | |
| SCHEMBL9939750 | 0.67 | SMN1; SMN2 (0.57) | SMN1; SMN2 | |
| SCHEMBL7962014 | 0.67 | SMN1; SMN2 (0.44) | SMN1; SMN2 | |
| SCHEMBL7952517 | 0.67 | SMN1; SMN2 (0.44) | SMN1; SMN2 | |
| SCHEMBL7960224 | 0.67 | SMN1; SMN2 (0.47) | SMN1; SMN2 | |
| SCHEMBL7951873 | 0.67 | SMN1; SMN2 (0.47) | SMN1; SMN2 | |
| SCHEMBL8025929 | 0.66 | SMN1; SMN2 (0.51) | SMN1; SMN2 | |
| SCHEMBL28711487 | 0.66 | SMN1; SMN2 (0.51) | SMN1; SMN2 | |
| SCHEMBL7964391 | 0.65 | SMN1; SMN2 (0.51) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211189-B1 | NITRIC OXIDE SYNTHASE INHIBITORS; ANTIINFLAMMATORY AGENTS, ANALGESICS | ASTRAZENECA UK LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| US-6083952-A | Compounds | ASTRA PHARMACEUTICALS LIMITED (GB) | 2000-07-04 | — | — | US | disclosed |
| EP-1000064-A1 | COMPOUNDS | AstraZeneca UK Limited (GB) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999001455-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-01-14 | — | — | WO | disclosed |