SCHEMBL7960667

SCHEMBL7960667

COC(C)(O)CCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
SSTR4 P31391 1/20 0.41
ALDH1A1 P00352 4/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
MAPT P10636 2/20 0.39
POLB P06746 1/20 0.39
FDPS P14324 1/20 0.38
NR3C1 P04150 1/20 0.38
ALOX12 P18054 2/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 2/20 0.38
HTT P42858 2/20 0.38
KMT2A Q03164 2/20 0.38
SLC13A5 Q86YT5 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1357605 0.79 SLC6A2 (0.50) ALDH1A1SMN1; SMN2FDPSNR3C1TAAR1
SCHEMBL19509051 0.79 ALDH1A1 (0.41) TDP1ALDH1A1SMN1; SMN2MAPTALOX12
SCHEMBL22781499 0.79 FDPS (0.55) TDP1NPC1RAB9AFDPSL3MBTL1
SCHEMBL251220 0.79 TDP1 (0.48) TDP1ALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL272368 0.79 TDP1 (0.48) TDP1ALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL28112277 0.79 TDP1 (0.48) TDP1SSTR4ALDH1A1SMN1; SMN2NPC1
SCHEMBL6554382 0.77 ALDH1A1 (0.42) TDP1ALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL7277922 0.77 TP53 (0.44) TDP1ALDH1A1SMN1; SMN2ALOX12HPGD
Water SCHEMBL27475250 0.77 TDP1 (0.46) TDP1ALDH1A1SMN1; SMN2NPC1RAB9A
Ammonia Solution, Strong SCHEMBL2333633 0.77 TDP1 (0.46) TDP1ALDH1A1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6225281-B1 HIGH PURITY GEOMETRIC ISOMER OBTAINED BY MACROLACTONIZATION OF CIS-16-HYDROXY-9-HEXADECENOIC ACID OR THE ESTER; FRAGRANCES SYNAROME (FR) 2001-05-01 US disclosed
US-6150538-A PEROXIDATION AND ACIDIFICATION TO FORM EPOXIDES, HYDROLYSIS TO FORM ERYTHROALEURITIC ACID OR ESTER, HEATING WITH ORTHO ESTER TO FORM DIOXOLANE AND PYROLYSIS TO FORM HYDROXYHEXADECANOIC ACID THEN MACROLACTONIZATION SYNAROME (FR) 2000-11-21 US disclosed