SCHEMBL6554382

SCHEMBL6554382

COC(CCc1ccccc1)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TAAR1 Q96RJ0 3/20 0.41
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
IDO1 P14902 1/20 0.39
AOC3 Q16853 1/20 0.39
LTA4H P09960 1/20 0.39
TP53 P04637 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28927876 0.88 ALDH1A1 (0.37) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL7277922 0.86 TP53 (0.44) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL19509051 0.80 ALDH1A1 (0.41) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL6023404 0.78 TP53 (0.41) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL7960667 0.77 TDP1 (0.41) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL10920935 0.77 ALDH1A1 (0.38) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL5088767 0.76 SLC6A2 (0.50) ALDH1A1TAAR1SMN1; SMN2IDO1LTA4H
SCHEMBL10877063 0.75 ALDH1A1 (0.35) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL813451 0.74 ALDH1A1 (0.39) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL11146281 0.74 SPHK2 (0.46) TAAR1CYP2A6HTR2ASMN1; SMN2LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487770-A1 FORMATION OF NEOLIGNAN BY DDQ MEDIATED DIMERISATION OF DIHYDROASARONE Council of Scientific and Industrial Research;an Indian Reg. body incorporated under Reg. of Societies Act (Act XXI of 1860) (IN) 2004-12-22 EP disclosed
WO-2003080551-A1 FORMATION OF NEOLIGNAN BY DDQ MEDIATED DIMERISATION OF DIHYDROASARONE COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-02 WO disclosed
WO-2002072709-A1 A PROCESS FOR THE PREPARATION OF SUBSTITUTED TRANS-CINNAMALDEHYDE, A NATURAL YELLOW DYE, FROM PHENYLPROPANE DERIVATIVES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-09-19 WO disclosed