Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.67 |
| ▸ | F9 | P00740 | 4/20 | 0.67 |
| ▸ | F7 | P08709 | 4/20 | 0.67 |
| ▸ | F11 | P03951 | 3/20 | 0.67 |
| ▸ | F2 | P00734 | 7/20 | 0.48 |
| ▸ | PLAU | P00749 | 7/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.48 |
| ▸ | PLG | P00747 | 6/20 | 0.48 |
| ▸ | PLAT | P00750 | 4/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.41 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.41 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20307774 | 0.89 | F10 (0.67) | F10F9F7F11F2 | |
| SCHEMBL7969187 | 0.89 | F10 (0.67) | F10F9F7F11F2 | |
| SCHEMBL7973134 | 0.89 | F10 (0.64) | F10F9F7F11F2 | |
| SCHEMBL7976836 | 0.88 | F10 (0.54) | F10F9F7F11F2 | |
| SCHEMBL1232343 | 0.82 | F10 (0.84) | F10F9F7F11F2 | |
| SCHEMBL20307797 | 0.82 | F9 (0.47) | F10F9F7F11CHEK2 | |
| SCHEMBL7982567 | 0.81 | F10 (0.58) | F10F9F7F11F2 | |
| SCHEMBL10172686 | 0.81 | CHEK2 (0.69) | F10F9F7F11CHEK2 | |
| SCHEMBL7973887 | 0.81 | F10 (0.70) | F10F9F7F11F2 | |
| SCHEMBL7973776 | 0.81 | F10 (1.00) | F10F9F7F11F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |