Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 10/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977075 | 0.91 | LTB4R2 (0.46) | BDKRB1ALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL3977563 | 0.86 | BDKRB1 (0.52) | BDKRB1GAAALDH1A1KDM4EHPGD | |
| SCHEMBL3976517 | 0.84 | BDKRB1 (0.48) | BDKRB1GAAALDH1A1KDM4EHPGD | |
| SCHEMBL3978885 | 0.82 | BDKRB1 (0.49) | BDKRB1ALDH1A1KDM4EHPGDCRHBP | |
| SCHEMBL8419112 | 0.80 | L3MBTL1 (0.45) | GAAALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL3974833 | 0.80 | ALDH1A1 (0.42) | BDKRB1GAAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL2927336 | 0.79 | BDKRB1 (0.49) | BDKRB1ALDH1A1KDM4EHPGDCRHBP | |
| SCHEMBL3982611 | 0.78 | ALDH1A1 (0.43) | BDKRB1GAAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7960900 | 0.77 | BDKRB1 (0.42) | BDKRB1ALDH1A1KDM4EHPGDCRHBP | |
| SCHEMBL2598198 | 0.76 | BDKRB1 (0.47) | BDKRB1ALDH1A1KDM4EHPGDCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232334-B1 | HAVE POTENT ANGIOTENSIN II ANTAGONISTIC ACTIVITY AND ANTIHYPERTENSIVE ACTIVITY, FOR TREATING CIRCULATORY SYSTEM DISEASES SUCH AS HYPERTENSIVE DISEASES, HEART DISEASES, STROKES, CEREBRAL APOPLEXY AND NEPHRITIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| US-6004989-A | ETHYL 2-ETHOXY-1-(2'-1H-TETRAZOL-5-YL)BIPHENYL-4-YL)METHYL) BENZIMIDAZOLE-7-CARBOXYLATE AND SALTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-21 | — | — | US | disclosed |