Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960903 | 0.80 | BDKRB1 (0.47) | L3MBTL1POLBUSP2ALDH1A1KDM4E | |
| SCHEMBL3977075 | 0.78 | LTB4R2 (0.46) | L3MBTL1POLBUSP2ALDH1A1TSHR | |
| SCHEMBL8419109 | 0.78 | FFAR1 (0.39) | L3MBTL1FFAR1AKR1B1ALDH1A1TSHR | |
| SCHEMBL8421301 | 0.74 | RAB9A (0.48) | L3MBTL1FFAR1AKR1B1ALDH1A1TSHR | |
| SCHEMBL27453802 | 0.71 | FFAR1 (0.53) | FFAR1AKR1B1ALDH1A1TSHRHPGD | |
| SCHEMBL7376271 | 0.71 | ALDH1A1 (0.42) | L3MBTL1FFAR1AKR1B1ALDH1A1TSHR | |
| SCHEMBL9339237 | 0.71 | PPARG (0.46) | — | |
| SCHEMBL18998062 | 0.70 | FFAR1 (0.45) | L3MBTL1FFAR1AKR1B1ALDH1A1TSHR | |
| SCHEMBL3974833 | 0.69 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1CYP3A4TDP1MAPK1 | |
| SCHEMBL4008849 | 0.69 | FFAR1 (0.57) | L3MBTL1FFAR1AKR1B1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962491-A | ANGIOTENSIN ANTAGONIST, HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS, STROKES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |