Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7961185 | 0.79 | HTT (0.38) | HTTSLC9A1MEN1KMT2ATP53 | |
| SCHEMBL24366443 | 0.73 | GID4 (0.40) | MEN1KMT2AKDM1ARCOR1ALDH1A1 | |
| SCHEMBL6119918 | 0.72 | KDM1A (0.34) | TP53KDM1AALDH1A1MAPTHPGD | |
| SCHEMBL6119978 | 0.72 | KDM1A (0.34) | TP53KDM1AALDH1A1MAPTHPGD | |
| SCHEMBL8221834 | 0.70 | KDM1A (0.43) | HTTSLC9A1MEN1KMT2AKDM1A | |
| SCHEMBL22467373 | 0.68 | SLC6A3 (0.43) | HTTSLC9A1TP53SLC6A3MDM2 | |
| SCHEMBL22467371 | 0.68 | SLC6A3 (0.43) | HTTSLC9A1TP53SLC6A3MDM2 | |
| SCHEMBL22490013 | 0.68 | SLC6A3 (0.43) | HTTSLC9A1TP53SLC6A3MDM2 | |
| SCHEMBL26870987 | 0.66 | GSK3B (0.47) | KMT2ATP53ALDH1A1MAPTHPGD | |
| SCHEMBL1072730 | 0.65 | SLC6A3 (0.54) | MEN1KMT2AMAPTSLC6A3GID4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323222-B1 | COGNITION ACTIVATORS, ALZHEIMER*S DISEASE AND ENZYME INHIBITORS | ADIR ET COMPAGNIE (FR) | 2001-11-27 | — | — | US | disclosed |