Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961254 | 1.00 | FFAR1 (0.49) | FFAR1CYP2D6MTNR1AMTNR1BSLC6A2 | |
| SCHEMBL8301035 | 0.88 | PPARG (0.43) | FFAR1PPARGPPARA | |
| SCHEMBL7956194 | 0.84 | CYP1A2 (0.53) | FFAR1MTNR1AMTNR1BSLC6A3PPARG | |
| SCHEMBL7956197 | 0.84 | CYP1A2 (0.53) | FFAR1MTNR1AMTNR1BSLC6A3PPARG | |
| SCHEMBL8166235 | 0.82 | PPARG (0.46) | FFAR1MTNR1AMTNR1BSLC6A2SLC6A3 | |
| SCHEMBL31758112 | 0.80 | FFAR1 (0.41) | FFAR1SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL29960692 | 0.79 | ALDH1A1 (0.39) | CYP2D6SLC6A2SLC6A3SLC6A4MEN1 | |
| SCHEMBL23934473 | 0.79 | CYP2D6 (0.47) | FFAR1CYP2D6SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8298173 | 0.78 | PPARA (0.53) | PPARGPPARA | |
| SCHEMBL8802816 | 0.76 | TSHR (0.50) | FFAR1MEN1KMT2ACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262060-B1 | TREATMENT OF HYPERGLYCAEMIA, DIABETES, OBESITY OR INFLAMMATION | SANOFI-SYNTHELABO (FR) | 2001-07-17 | — | — | US | disclosed |