Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31758112 | 0.86 | FFAR1 (0.41) | PPARGPPARAFFAR1DRD2SLC6A2 | |
| SCHEMBL8301035 | 0.86 | PPARG (0.43) | PPARGPPARAFFAR1PIN1 | |
| SCHEMBL7961254 | 0.82 | FFAR1 (0.49) | PPARGPPARATSHRFFAR1MTNR1A | |
| SCHEMBL7961253 | 0.82 | FFAR1 (0.49) | PPARGPPARATSHRFFAR1MTNR1A | |
| SCHEMBL10742068 | 0.82 | TSHR (0.43) | TSHRFFAR1L3MBTL1PIN1HPGD | |
| SCHEMBL13925659 | 0.82 | ESR1 (0.56) | PPARGPPARADRD2MTNR1AMTNR1B | |
| SCHEMBL31072342 | 0.80 | MTNR1B (0.52) | MTNR1AMTNR1B | |
| SCHEMBL10493642 | 0.79 | ACE (0.42) | PPARGPPARATSHRFFAR1MTNR1A | |
| SCHEMBL10493648 | 0.79 | ACE (0.42) | PPARGPPARATSHRFFAR1MTNR1A | |
| SCHEMBL31757646 | 0.79 | MEN1 (0.39) | PPARGPPARATSHRFFAR1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048852-A | BACTERICIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-04-11 | — | — | US | disclosed |
| EP-0900197-A1 | BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997030027-A1 | BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-21 | — | — | WO | disclosed |
| US-4249021-A | USEFUL AS DIURETIC AGENTS IN TREATMENT OF EDEMA; ALSO FOR TREATMENT OF HYPERTENSION | MERCK & CO., INC. (US) | 1981-02-03 | — | — | US | disclosed |