SCHEMBL8301035

SCHEMBL8301035

CCOC(=O)C(CC)C1CCc2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARG P37231 14/20 0.43
PPARA Q07869 13/20 0.43
PIN1 Q13526 1/20 0.42
FFAR1 O14842 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7961253 0.88 FFAR1 (0.49) PPARGPPARAFFAR1
SCHEMBL7961254 0.88 FFAR1 (0.49) PPARGPPARAFFAR1
SCHEMBL5726924 0.86 PIN1 (0.43) PPARGPPARAPIN1
SCHEMBL8166235 0.86 PPARG (0.46) PPARGPPARAPIN1FFAR1
SCHEMBL8298173 0.84 PPARA (0.53) PPARGPPARA
SCHEMBL31758112 0.83 FFAR1 (0.41) PPARGPPARAPIN1FFAR1
SCHEMBL820829 0.83 ESR1 (0.57) PPARGPPARA
SCHEMBL23934473 0.82 CYP2D6 (0.47) FFAR1
SCHEMBL23934517 0.79 NFE2L2 (0.38) PPARGPPARAFFAR1
SCHEMBL23699443 0.77 USP2 (0.43) PIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023205458-A2 FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-26 WO claimed
EP-0661273-B1 Indane derivatives and processes for preparing the same TANABE SEIYAKU CO (JP) 1999-05-19 EP disclosed
US-5686452-A PROTECTING FROM ENDOTOXIN SHOCK; TREATMENT OF NEPHRITIS TANABE SEIYAKU CO., LTD. (JP) 1997-11-11 US disclosed
CN-1107844-A Indane derivative, processes for preparing the same and synthetic intermediate of the same TANABE SEIYAKU CO (JP) 1995-09-06 CN disclosed
EP-0661273-A1 Indane derivative and processes for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1995-07-05 EP disclosed