Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947733 | 0.76 | HRH3 (0.55) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL7957253 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL29497715 | 0.67 | KMT2A (0.58) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL11154695 | 0.67 | ALDH1A1 (0.61) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL18711334 | 0.66 | ALDH1A1 (0.75) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14263482 | 0.66 | LMNA (0.44) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL3262200 | 0.66 | HRH3 (0.52) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL13034130 | 0.65 | GAA (0.49) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL11068898 | 0.64 | NOTUM (0.59) | ALDH1A1HPGD | |
| SCHEMBL6935906 | 0.64 | ALDH1A1 (0.72) | ALDH1A1HPGDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271234-B1 | DERIVATIVES WHICH BIND TO SEROTONERGIC RECEPTORS; TREATING DISORDERS OF THE LOWER URINARY TRACT | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2001-08-07 | — | — | US | disclosed |