Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154695 | 0.87 | ALDH1A1 (0.61) | HRH3LMNAKMT2AMEN1ATM | |
| SCHEMBL3262200 | 0.86 | HRH3 (0.52) | HRH3LMNAKMT2AMEN1ATM | |
| SCHEMBL6935906 | 0.83 | ALDH1A1 (0.72) | LMNADRD2DRD4KMT2AMEN1 | |
| SCHEMBL18917684 | 0.81 | VEGFA (0.59) | DRD2DRD4KMT2AMEN1ALDH1A1 | |
| SCHEMBL23230116 | 0.81 | HRH3 (0.53) | HRH3LMNAKMT2AMEN1ATM | |
| SCHEMBL7957253 | 0.79 | ALDH1A1 (0.45) | LMNAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL21802509 | 0.78 | MGLL (0.53) | HRH3LMNAKMT2AMEN1ATM | |
| SCHEMBL7961532 | 0.76 | ALDH1A1 (0.42) | LMNAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL30596568 | 0.76 | MEN1 (0.60) | HRH3DRD2KMT2AMEN1ALDH1A1 | |
| SCHEMBL15277893 | 0.74 | MGLL (0.50) | HRH3LMNAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271234-B1 | DERIVATIVES WHICH BIND TO SEROTONERGIC RECEPTORS; TREATING DISORDERS OF THE LOWER URINARY TRACT | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2001-08-07 | — | — | US | disclosed |