Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1844172 | 0.80 | GAA (0.40) | GAAUSP2TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL12410539 | 0.73 | ALDH1A1 (0.36) | GAAUSP2TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL16950194 | 0.71 | TSHR (0.42) | GAAUSP2TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL21485110 | 0.70 | GAA (0.37) | GAAUSP2TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7964378 | 0.69 | ALDH1A1 (0.41) | ALDH1A1BRD4MIFMAPT | |
| SCHEMBL7961617 | 0.67 | GAA (0.40) | GAAUSP2TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7403091 | 0.66 | LMNA (0.59) | TSHRALDH1A1SMN1; SMN2HSD17B10HTT | |
| SCHEMBL17070546 | 0.65 | USP2 (0.41) | GAAUSP2TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL10932127 | 0.62 | CYP2D6 (0.41) | GAAUSP2TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL18916559 | 0.62 | GLS (0.47) | GAAUSP2TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |