Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 9/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | TK2 | O00142 | 7/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963954 | 0.72 | TK1 (0.38) | TK1ELANEKIF11TK2DUT | |
| SCHEMBL4755817 | 0.70 | — | — | |
| SCHEMBL2207349 | 0.70 | KIF11 (0.39) | TK1ELANEKIF11TK2CYP2C9 | |
| SCHEMBL19621223 | 0.66 | KIF11 (0.41) | TK1ELANEKIF11TK2CYP2C9 | |
| SCHEMBL19020598 | 0.64 | KIF11 (0.46) | TK1KIF11TK2MEN1KMT2A | |
| SCHEMBL1092597 | 0.64 | KIF11 (0.54) | TK1KIF11CYP2C9TSHRCYP2C19 | |
| SCHEMBL15867168 | 0.63 | — | — | |
| SCHEMBL28791230 | 0.62 | KIF11 (0.47) | TK1ELANEKIF11TK2CYP2C9 | |
| SCHEMBL2522162 | 0.62 | CYP2C9 (0.48) | TK1ELANEKIF11TK2CYP2C9 | |
| SCHEMBL19020517 | 0.62 | KIF11 (0.43) | TK1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255339-B1 | PREVENTION PROSGESTERONE RECEPTOR BINDING | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0885893-A1 | NOVEL TETRAHYDRONAPHTHOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |