Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 7/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TK2 | O00142 | 9/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961625 | 0.72 | TK1 (0.39) | TK1ELANETK2KIF11DUT | |
| SCHEMBL19020598 | 0.66 | KIF11 (0.46) | TK1TK2KIF11 | |
| SCHEMBL7963957 | 0.65 | TK2 (0.39) | TK1TK2KIF11 | |
| SCHEMBL24830185 | 0.63 | CYP3A4 (0.38) | TK1ELANETK2KIF11 | |
| SCHEMBL19020520 | 0.63 | TP53 (0.48) | TK1ELANEKIF11 | |
| SCHEMBL8839396 | 0.63 | KCNH3 (0.42) | KIF11DUT | |
| SCHEMBL2207349 | 0.63 | KIF11 (0.39) | TK1ELANETK2KIF11DUT | |
| SCHEMBL7696589 | 0.63 | KCNH3 (0.42) | KIF11DUT | |
| SCHEMBL1092597 | 0.63 | KIF11 (0.54) | TK1KIF11 | |
| SCHEMBL17398262 | 0.62 | ELANE (0.41) | TK1ELANETK2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255339-B1 | PREVENTION PROSGESTERONE RECEPTOR BINDING | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0885893-A1 | NOVEL TETRAHYDRONAPHTHOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |