Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 16/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 16/20 | 1.00 |
| ▸ | RELA | Q04206 | 16/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971958 | 0.88 | NFKB1 (0.77) | NFKB1NFKB2RELAABCB1 | |
| SCHEMBL25187265 | 0.82 | NFKB1 (0.69) | NFKB1NFKB2RELAABCB1 | |
| SCHEMBL25264495 | 0.82 | NFKB1 (0.69) | NFKB1NFKB2RELAABCB1 | |
| SCHEMBL8934605 | 0.77 | NFKB1 (0.63) | NFKB1NFKB2RELATUBB4ATUBB | |
| SCHEMBL7351311 | 0.73 | NFKB1 (0.57) | NFKB1NFKB2RELATUBB4ATUBB | |
| SCHEMBL6493076 | 0.71 | NFKB1 (0.55) | NFKB1NFKB2RELA | |
| SCHEMBL7961876 | 0.71 | NFKB1 (0.76) | NFKB1NFKB2RELAABCB1 | |
| SCHEMBL7975443 | 0.71 | NFKB1 (1.00) | NFKB1NFKB2RELAABCB1 | |
| SCHEMBL7975362 | 0.71 | NFKB1 (1.00) | NFKB1NFKB2RELAABCB1 | |
| SCHEMBL25197813 | 0.70 | NFKB1 (0.54) | NFKB1NFKB2RELAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624190-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2017-04-18 | — | — | US | disclosed |
| WO-2001072735-A2 | BENZOPYRANES USEFUL AS TNF ALPHA INHIBITORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-04 | — | — | WO | disclosed |