SCHEMBL7961869 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	PGR	P06401	2/20	0.34

▸	MEN1	O00255	1/20	0.33

▸	ALDH1A1	P00352	1/20	0.33

▸	GAA	P10253	1/20	0.33

▸	KMT2A	Q03164	1/20	0.33

▸	TDP2	O95551	1/20	0.32

▸	PRKDC	P78527	1/20	0.32

▸	RAF1	P04049	1/20	0.31

▸	KDM4E	B2RXH2	2/20	0.31

▸	HTT	P42858	1/20	0.30

▸	ATM	Q13315	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7948284	0.86	TDP2 (0.33)	PGRTDP2PRKDC
SCHEMBL12245945	0.86	PGR (0.31)	PGRTDP2PRKDC
SCHEMBL7959910	0.82	KDM4E (0.46)	ALDH1A1GAAKMT2ATDP2RAF1
SCHEMBL2375582	0.73	BACE1 (0.41)	PGRPRKDC
SCHEMBL2375588	0.73	BACE1 (0.41)	PGRPRKDC
SCHEMBL7965367	0.68	KDM4E (0.46)	ALDH1A1GAAKMT2ARAF1KDM4E
SCHEMBL7959633	0.68	KDM4E (0.33)	ALDH1A1KDM4EHTTATM
SCHEMBL1819491	0.67	KDM4E (0.54)	ALDH1A1GAAKMT2AKDM4EHTT
SCHEMBL30410537	0.67	LMNA (0.36)	HTT
SCHEMBL1822380	0.66	PGR (0.50)	PGRPRKDCRAF1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010021680-A2	INHIBITORS OF BETA-SECRETASE	VITAE PHARMACEUTICALS, INC. (US)	2010-02-25	—	—	WO	disclosed