Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065415 | 0.86 | — | — | |
| SCHEMBL7952010 | 0.83 | ALDH1A1 (0.35) | ALDH1A1LMNARARGIKBKBRARA | |
| SCHEMBL7964173 | 0.82 | RARA (0.38) | ALDH1A1KDM4ERARGIKBKBRARA | |
| SCHEMBL7964175 | 0.82 | RARA (0.38) | ALDH1A1KDM4ERARGIKBKBRARA | |
| SCHEMBL31037190 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL7959829 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHRTDP1LMNARARG | |
| SCHEMBL7951953 | 0.81 | ALDH1A1 (0.34) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL7962499 | 0.78 | ALDH1A1 (0.35) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL7951806 | 0.78 | FDPS (0.41) | ALDH1A1TSHRTDP1LMNAIKBKB | |
| SCHEMBL7963270 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KDM4ETSHRTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313305-B1 | ANTIBIOTICS, BACTERICIDES | HOECHST MARION ROUSSEL (FR) | 2001-11-06 | — | — | US | disclosed |
| US-5587372-A | BACERICIDES | ROUSSEL UCLAF (FR) | 1996-12-24 | — | — | US | disclosed |