Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947839 | 0.88 | KDM4E (0.32) | KDM4EMAPTATML3MBTL1 | |
| SCHEMBL7962464 | 0.82 | BACE1 (0.33) | KDM4EMAPT | |
| SCHEMBL12299286 | 0.72 | AR (0.35) | — | |
| SCHEMBL7960735 | 0.72 | CYP19A1 (0.34) | KDM4EMAPT | |
| SCHEMBL7948351 | 0.69 | KDM4E (0.34) | KDM4EMAPTATML3MBTL1 | |
| SCHEMBL12299287 | 0.69 | KDM4E (0.34) | KDM4EMAPTATML3MBTL1 | |
| SCHEMBL7958731 | 0.66 | FADS1 (0.37) | — | |
| SCHEMBL12299271 | 0.65 | AKR1B1 (0.33) | — | |
| SCHEMBL7710613 | 0.62 | CYP11B1 (0.38) | — | |
| 6-Bromo-2-(Thiophen-2-Yl)Chroman-4-One SCHEMBL1824814 | 0.62 | AR (0.58) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |