Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21703526 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL22938904 | 0.77 | APP (0.41) | ALDH1A1RAB9ASMN1; SMN2LMNAMAOB | |
| SCHEMBL9731911 | 0.77 | ALDH1A1 (0.53) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL19746 | 0.77 | CYP19A1 (0.45) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL11733122 | 0.76 | CYP19A1 (0.44) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| Methane SCHEMBL27973705 | 0.76 | CYP19A1 (0.44) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL120709 | 0.74 | MEN1 (0.48) | ALDH1A1CA2KDM4EMAPTPOLB | |
| SCHEMBL8207399 | 0.72 | MEN1 (0.47) | ALDH1A1CA2KDM4EMAPTPOLB | |
| SCHEMBL31650964 | 0.72 | ALDH1A1 (0.56) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| Methoxymethane SCHEMBL27610365 | 0.72 | KDM4E (0.42) | ALDH1A1CA2RAB9AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |