Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962169 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL9731911 | 0.74 | ALDH1A1 (0.53) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL120709 | 0.71 | MEN1 (0.48) | ALDH1A1CA2KDM4EMAPTPOLB | |
| SCHEMBL8207399 | 0.69 | MEN1 (0.47) | ALDH1A1CA2KDM4EMAPTPOLB | |
| SCHEMBL7252825 | 0.69 | ALDH1A1 (0.42) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL31650964 | 0.69 | ALDH1A1 (0.56) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL29253910 | 0.69 | KDM4E (0.45) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL9303316 | 0.69 | ALDH1A1 (0.43) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL28452557 | 0.68 | ALDH1A1 (0.54) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL983728 | 0.68 | ALDH1A1 (0.54) | ALDH1A1CA2RAB9ASLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844050-B2 | Cyclization processes of hydroxyalkenoic acids and products thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2020-11-24 | — | — | US | disclosed |
| US-20200048233-A1 | CYCLIZATION PROCESSES OF HYDROXYALKENOIC AICDS AND PRODUCTS THEREOF | Yissum Research Development Company, of The Hebrew University of Jerusalem Ltd. (IL) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844050-B2 | Cyclization processes of hydroxyalkenoic acids and products thereof | FASN, ALOX5, HACL2 | ALDH1A1 387/4885CA2 2445/4885RAB9A 4217/4885 |
| US-20200048233-A1 | CYCLIZATION PROCESSES OF HYDROXYALKENOIC AICDS AND PRODUCTS THEREOF | FADS2, FASN, ACADM | ALDH1A1 188/4885CA2 1758/4885RAB9A 4181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.