Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 7/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5959250 | 0.74 | TP53 (0.53) | UNGTP53MAPTHPGDXBP1 | |
| SCHEMBL2416578 | 0.74 | LMNA (0.50) | UNGTP53MAPTHSD17B10LMNA | |
| SCHEMBL10156550 | 0.74 | POLB (0.48) | MAPTLMNAPOLB | |
| SCHEMBL10156704 | 0.73 | ROCK1 (0.45) | MAPTHPGDSMN1; SMN2POLB | |
| SCHEMBL1506784 | 0.73 | UNG (1.00) | UNGGPR84 | |
| SCHEMBL7950536 | 0.73 | UNG (1.00) | UNGGPR84 | |
| SCHEMBL7962222 | 0.73 | UNG (1.00) | UNGGPR84 | |
| SCHEMBL7951048 | 0.71 | UNG (0.75) | UNGTP53MAPTHPGDXBP1 | |
| SCHEMBL7962178 | 0.71 | UNG (0.49) | UNGTP53MAPTHPGDXBP1 | |
| SCHEMBL1266331 | 0.70 | STK17A (0.54) | UNGTP53HSD17B10LMNAPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177437-B1 | VIRICIDES | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER | 2001-01-23 | — | — | US | disclosed |