Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714340 | 0.86 | KDM4E (0.59) | ALOX5KDM4ECYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4013917 | 0.86 | SLC11A2 (0.52) | ALOX5DRD4KDM4ESLC11A2AHR | |
| SCHEMBL787256 | 0.82 | ALOX5 (0.59) | ALOX5DRD4KDM4ESLC11A2AHR | |
| SCHEMBL17196260 | 0.81 | ALOX5 (0.58) | ALOX5DRD4KDM4ESLC11A2AHR | |
| SCHEMBL787558 | 0.81 | ALOX5 (0.54) | ALOX5DRD4KDM4ESLC11A2AHR | |
| SCHEMBL10109859 | 0.81 | ALOX5 (0.58) | ALOX5DRD4KDM4EAHRCYP19A1 | |
| SCHEMBL13201404 | 0.78 | ALDH1A1 (0.43) | ALOX5KDM4EAHRCYP19A1CYP11B1 | |
| SCHEMBL21436953 | 0.78 | ALOX5 (0.51) | ALOX5DRD4KDM4EAHRCYP19A1 | |
| SCHEMBL20982326 | 0.78 | ALOX5 (0.51) | ALOX5DRD4KDM4EMAPTPKM | |
| SCHEMBL8374054 | 0.78 | ALOX5 (0.55) | ALOX5DRD4KDM4ESLC11A2AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001077095-A2 | DERIVATIVES OF ALPHA-MERCAPTOACETAMIDE | NOVARTIS AG (CH) | 2001-10-18 | — | — | WO | disclosed |