Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 5/20 | 0.35 |
| ▸ | THRA | P10827 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126526 | 0.88 | HPGD (0.38) | HPGDF2ELANEXDHALDH1A1 | |
| SCHEMBL7962513 | 0.85 | HPGD (0.49) | HPGDF2ELANEXDH | |
| SCHEMBL7951445 | 0.83 | THRB (0.43) | F2ELANETHRBTHRAALDH1A1 | |
| SCHEMBL8747650 | 0.81 | F2 (0.39) | F2ELANETHRBTHRAALDH1A1 | |
| SCHEMBL8134797 | 0.80 | HPGD (0.36) | HPGDF2ELANEXDH | |
| SCHEMBL7962519 | 0.79 | HPGD (0.38) | HPGDF2ELANEXDHALDH1A1 | |
| SCHEMBL8119631 | 0.79 | STING1 (0.44) | HPGDF2ELANEXDHALDH1A1 | |
| SCHEMBL7962974 | 0.77 | HPGD (0.36) | HPGDF2ELANEXDHRARA | |
| SCHEMBL7962968 | 0.77 | HPGD (0.36) | HPGDF2ELANEXDHALDH1A1 | |
| SCHEMBL7951509 | 0.77 | FDPS (0.38) | HPGDXDHALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313305-B1 | ANTIBIOTICS, BACTERICIDES | HOECHST MARION ROUSSEL (FR) | 2001-11-06 | — | — | US | disclosed |
| US-5455238-A | Bactericides | ROUSSEL UCLAF (FR) | 1995-10-03 | — | — | US | disclosed |