Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 6/20 | 0.37 |
| ▸ | THRA | P10827 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119126 | 0.88 | RARG (0.35) | F2ELANERARGFFAR4FFAR1 | |
| SCHEMBL7951445 | 0.86 | THRB (0.43) | F2ELANERARGTHRBTHRA | |
| SCHEMBL3641084 | 0.83 | GAA (0.47) | F2ELANERARGGAAALDH1A1 | |
| SCHEMBL7964642 | 0.82 | F2 (0.41) | F2ELANERARGGAAFFAR4 | |
| SCHEMBL7962583 | 0.81 | HPGD (0.44) | F2ELANERARGTHRBTHRA | |
| SCHEMBL8747666 | 0.79 | RARG (0.31) | RARG | |
| SCHEMBL8129787 | 0.78 | RARG (0.35) | F2ELANERARGFFAR4FFAR1 | |
| SCHEMBL7962141 | 0.78 | BLM (0.37) | F2ELANERARGTSHRFFAR4 | |
| SCHEMBL8118651 | 0.77 | STING1 (0.44) | F2ELANERARGGAAALDH1A1 | |
| SCHEMBL3637864 | 0.76 | CA5A (0.56) | F2ELANEGAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761672-A1 | Cephalosporin containing in position 7 a substituted benzyloxyimino radical, processes for their preparation and intermediates for their preparation, their use as medicaments | ROUSSEL UCLAF (FR) | 1997-03-12 | — | — | EP | disclosed |