Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | IKBKB | O14920 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124909 | 0.86 | PTPN1 (0.59) | PTPN1LMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL7962553 | 0.84 | RARG (0.36) | PTPN1IKBKBHIF1AF2ELANE | |
| SCHEMBL7951479 | 0.81 | SMN1; SMN2 (0.50) | PTPN1LMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL7962589 | 0.78 | PTPN1 (0.47) | PTPN1LMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL8128464 | 0.77 | FABP4 (0.38) | PTPN1LMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL8125348 | 0.77 | PTPN1 (0.37) | PTPN1LMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL8119171 | 0.77 | CASP3 (0.36) | PTPN1L3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7951484 | 0.76 | FABP4 (0.50) | PTPN1LMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL10971500 | 0.76 | SMN1; SMN2 (0.60) | LMNAL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8649507 | 0.76 | PTPN1 (0.36) | PTPN1LMNAL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313305-B1 | ANTIBIOTICS, BACTERICIDES | HOECHST MARION ROUSSEL (FR) | 2001-11-06 | — | — | US | disclosed |
| US-5587372-A | BACERICIDES | ROUSSEL UCLAF (FR) | 1996-12-24 | — | — | US | disclosed |
| US-5455238-A | Bactericides | ROUSSEL UCLAF (FR) | 1995-10-03 | — | — | US | disclosed |