Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | IKBKB | O14920 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380425 | 0.83 | RARG (0.35) | LMNAKMT2AIKBKBALDH1A1MEN1 | |
| SCHEMBL8378662 | 0.81 | HPGD (0.33) | PTPN1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL7962591 | 0.76 | PTPN1 (0.44) | PTPN1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL8124909 | 0.76 | PTPN1 (0.59) | PTPN1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL7951479 | 0.73 | SMN1; SMN2 (0.50) | PTPN1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL7951484 | 0.69 | FABP4 (0.50) | PTPN1L3MBTL1LMNAMAPTIKBKB | |
| SCHEMBL7962571 | 0.69 | FABP4 (0.50) | PTPN1L3MBTL1LMNAMAPTIKBKB | |
| SCHEMBL7962589 | 0.69 | PTPN1 (0.47) | PTPN1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL8128464 | 0.68 | FABP4 (0.38) | PTPN1L3MBTL1LMNAMAPTIKBKB | |
| SCHEMBL7959833 | 0.67 | RARG (0.35) | IKBKBRARAF2ELANERARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763617-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5728828-A | A 3-(3-CHLORO- OR IODOPROP-1-EN-1-YL),7-(2-AMINOTHIAZOL-4-YL) ((CARBOXY)(PHENYL)METHOXYIMINO)ACETAMIDO-3-CEPHEM; GRAMNEGATIVE AND -POSITIVE BACTERIA, ESP. ANTIBIOTIC-RESISTANCE STAPHYLOCOCCUS | ROUSSEL UCLAF (FR) | 1998-03-17 | — | — | US | disclosed |