Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5812524 | 0.86 | SLC6A4 (0.53) | SLC6A2SLC6A3SLC6A4LTA4HPPARG | |
| SCHEMBL6357746 | 0.86 | SLC6A4 (0.53) | SLC6A2SLC6A3SLC6A4LTA4HPPARG | |
| SCHEMBL540925 | 0.84 | SLC6A4 (0.52) | SLC6A2SLC6A3SLC6A4CTSCLTA4H | |
| SCHEMBL7950513 | 0.83 | TRPA1 (0.47) | LTA4HDPP4LAP3ANPEPRNPEP | |
| SCHEMBL6321788 | 0.82 | ALPI (0.58) | SLC6A2SLC6A3SLC6A4LTA4HLAP3 | |
| SCHEMBL7959353 | 0.82 | ALPI (0.58) | SLC6A2SLC6A3SLC6A4LTA4HLAP3 | |
| SCHEMBL4654874 | 0.82 | SLC6A2 (0.59) | SLC6A2SLC6A3SLC6A4ACACBCTSC | |
| SCHEMBL12188513 | 0.82 | SLC6A2 (0.59) | SLC6A2SLC6A3SLC6A4ACACBCTSC | |
| SCHEMBL12104067 | 0.82 | SLC6A2 (0.59) | SLC6A2SLC6A3SLC6A4ACACBCTSC | |
| SCHEMBL7951057 | 0.81 | PNMT (0.58) | LAP3ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1169791-C | Novel acetamide derivatives and protease inhibitors | �ձ���ҩ��ʽ���� | 2004-10-06 | — | — | CN | disclosed |
| US-6271238-B1 | USEFUL IN TREATING AND PREVENTING DISEASES INVOLVING CHYMOTRYPSIN TYPE PROTEASES WHICH ARE RELATED TO ASTHMA, ALLERGY, INFLAMMATIONS, RHEUMATISM, HYPERTENSION, HEART FAILURE, MYOCARDIAL INFARCTION, AND CARDIAC HYPERTROPHY | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-08-07 | — | — | US | disclosed |
| CN-1229405-A | Novel acetamide derivatives and protease inhibitors | NIPPON KAYAKU KK (JP) | 1999-09-22 | — | — | CN | disclosed |
| EP-0936216-A1 | NOVEL ACETAMIDE DERIVATIVES AND PROTEASE INHIBITORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-08-18 | — | — | EP | disclosed |