Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 8/20 | 0.58 |
| ▸ | S1PR4 | O95977 | 10/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 10/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221007 | 0.90 | GPR52 (0.71) | GPR52S1PR4S1PR5TP53 | |
| SCHEMBL7957670 | 0.82 | GPR52 (0.63) | GPR52S1PR4S1PR5 | |
| SCHEMBL3204292 | 0.77 | GPR52 (0.88) | GPR52S1PR4S1PR5TP53 | |
| SCHEMBL13489581 | 0.76 | GPR52 (0.81) | GPR52TP53 | |
| SCHEMBL1852050 | 0.76 | GPR52 (0.47) | GPR52S1PR4S1PR5TP53 | |
| SCHEMBL1850137 | 0.75 | GPR52 (0.69) | GPR52S1PR4S1PR5TP53 | |
| SCHEMBL1850988 | 0.74 | GPR52 (0.68) | GPR52S1PR4S1PR5TP53 | |
| SCHEMBL3198777 | 0.74 | GPR52 (1.00) | GPR52TP53 | |
| SCHEMBL29452903 | 0.74 | GPR52 (1.00) | GPR52TP53 | |
| SCHEMBL3210255 | 0.74 | GPR52 (0.76) | GPR52TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |